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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b458e3c681f5b42ee80f2868143985de85375b39d8d3fae9400d705c9e310920' 
  AND token = 'T8vBi4Ak1Kn2tm3GvWdX65DDd1catz45QdQNDzEu7Eg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}