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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3894e83e62a4d9239acb0daa699680c9f124ca9d889226c6c26c5c4b5bacfd63' 
  AND token = 'vQxkoVoSCpcbB6xM/OCeRFzkbN83Z5cvJBK+XfUrFwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}