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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85821cf98f201789e3aec3ac2dd4b4ba614391f3ba7188608675a3c31ab76f2d' 
  AND token = 'nqgTJM03UHUPGWIZHahhr0FNDb8o8WuPfuueYD2oy8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}