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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78fd3e1455bbaf9edd2ecb2d957dbfd8ad2f93cb9e20aef5e1b2a22e325c95f8' 
  AND token = 'W1cB85jMfdK5qSF3VRlMmvf/OmmUb27hWQcoP2pc98Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}