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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7e508023aae888e674f07d8c5b4869b22fe037e94f60a9a7cc8f7dc441ec121' 
  AND token = '5hn0FVfkv91Ry2gqaCYGklZo+bFLSlxjsuqvu8i38Uo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}