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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d6b4a711bbff171c052c8fb4c4e2d0be3138ec47fbb00e1c341c63765a6db12' 
  AND token = 'rY90q9AQmIkboGSF+/Yw0fXeU0nycrSFXolvwmcsOZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}