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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91f7181cdd81a7d68fb418dbffcebe0c6565d04ef8deefad2a1b2d6fbd8d3f66' 
  AND token = 'DeDUyNDuFfmAB4Cgxf2W7NxftXZPlzCkzEb2gSaYIf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}