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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0327951542ea61f02392c29abb20a38f05b476cae595dea9b62dd4d330697745' 
  AND token = 'vRS+WSnLagfslnWA5CfEgN2MfBIccDrTPUGW4hytQ7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}