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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f9e90d055fe2965dcb5537564b1c99cfd1b10ddb9c19df962bb322241291895' 
  AND token = 'w4NVeBQj6EeBhKH8f/AgLmk5KhizHVin2wf4vicR3vE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}