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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee6c840ba7523a1db5ca65805b95f7c1b51a141984b9bed32c3c1d13cc56a253' 
  AND token = 'jGlBgEvp0V5o+isTRB45U6aHantKQ/mjKe4zJMzVBnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}