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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e95ba4b37d6baf61f8c306550b6bc9a357090ebec3e0000e857eead9fc3f65b' 
  AND token = 'cpR3NNLu3u/Y1ATlqkGRDsAKhLQQbpy0SOayIjrTiMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}