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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad0e571f7ecb52365841a0f24234320a3e265c76820f3f587320d01357ea9f6f' 
  AND token = 'wURpf/pWx0tu6Me6d32obRy2AiYQcDjLdGw/mItSyRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}