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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '280422c4381f278d863cfe90938b952707c4808aff5b2a6b72348aa72e26d7bc' 
  AND token = 'WpUsYG1zJDcj8MIoWeAJOaLGwTmvpX6343F/75IlA70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}