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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2c9812980f9a8b1896382157477b4f7232394673a8db072f9d2e50cd5313ae4' 
  AND token = 'zHO0jeHCyuVmV0sLMD3Ld7SsPnkiiU1pShy30ROY/Fk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}