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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2dd7be29129d60ffe5e1094a750dd037dd111541ce4c2f034827433f603a256' 
  AND token = 'PXMlDbLGXNcFi/zaLF+679z0bEwi2Vzdys55waMTnbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}