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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d6685696e0f6edf2a9b60d439d573239a4af5edf8ad9eda0aa4bc024e8b0c25' 
  AND token = 'zBboizytJZLVOYfbXUDPhjba5PENLq24cmf5HTUJcgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}