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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b739a5a82c229b42fc571f4ca8b640879fa4214ef49d801272fc60dcf5e31e1' 
  AND token = 'mH1qdkHOi6LP8TnKxZ3A/RN8L8e8hOapG9D+3ayW93c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}