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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '014b4dde1d37730a1e669214153a92185c65408a5e7153384dd78e8b7cba75ce' 
  AND token = 'vK17kAwVy7PbJFgCsXk8SoGQIDjJqpUUa5LGHUNg6JU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}