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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '497c1fc79b9504124dd53efd681f5421da283c52aa53d93976916b810b438307' 
  AND token = 'KrNoC2X2OjV7X9mKierkmY7KeIPlirzS7dEobg8//cE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}