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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b774a2b3fbcbfb95c933872a06189cfc732f6c3e3a4a27b9a40fb70554646a72' 
  AND token = 'ElxTK/QgeF5Vgbye7xalZyn5kZ/3zYaAk5ysKWUlRGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}