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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c21962e33115783d57cfd0f9876ce8a33b771201cf0a1619159dff86b777706' 
  AND token = 'gTpWXU6PAaH41U7tDUEglJ2XY7X7pGTnPDHL/FgBLbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}