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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f81b683a48e33b744856363e6ab87a2ff28ceaf833e1d246741ef95f26c1ab1' 
  AND token = 'PCud6aW/nMKHTF3WFIIcaW0Jm0C1lx+WcD6SOKmWBO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}