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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '141f2c0dd3786db6af57809537a0432190dd0849ef1e20e98646833772ad1012' 
  AND token = 'PhF4ZEydNT/6+3NIjHQLQ8MZc4WmK5Sw5JKgY8SkoMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}