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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11321fe42559a71e87e804c152f15127f720baba6bcd1f8be3328d3cf5eeab32' 
  AND token = 'z6rJhogtbR20ty+HR6rcaUNcs4ov4tLbjVm+3vwKJrs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}