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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '697b50708ff8a93586a9b2421f7ff7e42d34e40ffc055c94e610ef0b7c20ae10' 
  AND token = '8u53/DPtBOI8UALYSHmaTDHPmxTdQwo2wl77mOrRVVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}