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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5e88f8ac104a65c48839bd25249fd58a6a529a6178703aa0f265879e842eda7' 
  AND token = 'dlr0sPaCAx0cEWzOsfxb0/VEtyO+eFnFzDjM+r4q+sk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}