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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f281d689c885cbb5aaa620ee46db2b931f93b7d8e482dd17dfc35c7619c3450d' 
  AND token = 'v/6AyIP3jzYKeHCLIK6xZcotAqlfxnb3xyRlpoIFP+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}