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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33a410e03d6bbeef2fc627ceb1d616a292db4451b40a56cb30e50d080085b592' 
  AND token = 'b0gNj4spIHO0TlH+H764nEF0CPmotrhl+9/7yPI351k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}