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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5627a6a26bf6951a50d8a411b9eea97538f83f20a8393d67f7130c1e1d060dc' 
  AND token = 'Ii5Ea8bAwIGZsyqq96cHNXx52CorMnFW0A4LByz9cU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}