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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8db00506ac13e0c6772fd187d84cd4a5d0904a51b0cb1133003c97a64d05827e' 
  AND token = 'B1zlLjjWvMq/mzt0Yt9MMO+2WIyn8rB54TRXe7gaLZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}