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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7c9b8e5b2c77dc35a4803644a8a76a5555965f32ed3d33728de716c709d082c' 
  AND token = 'PuIcIT6DQ+2fm60lOCqanCPsiF3HPuJw+LPU21lXQDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}