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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06f678740415a67a4e37b447065f1906f0710d901881fc03ed42ae448d79d60f' 
  AND token = 'rjmhTsT6b30U3byz0lel1kZiaTkjQxrO9XGBfY21yFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}