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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3cee4e3717a3fb5ecce04627fb3b7fa154f2a1c9cae831b9c4d8f27d22605fc' 
  AND token = 'yYCBdLicATZ38bvFXMDQpba6bnEUARdCsbAVs+LF+QU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}