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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57d0a5a24ac16ebdcd77dd2569215a955345f5ada2ee78fe9233f6f45e3af4c3' 
  AND token = 'a9m0+S7iGLkzL561mHo+/P3fNtsDzso1nr1/IVLZXHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}