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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdfb6e053b7d5170d263d88f77aa0c7dc19da45e8f21453ced507c9af3cb38dd' 
  AND token = 'R3RwInVNPqaUQZ+Mn3R5f00lIN08K/W8VOHtTmLxzIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}