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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '505c6422751b2cd430a2cc1e49b5bcdb51c7e9fa894df17fc91a0776a9f43331' 
  AND token = 'crCQQioI/t54F0eZRuRlPZmhtoU6aQK3IJLxtAOu+Kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}