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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80afa7ca6c36ac3b84c6117d3eebe92e006412d5310c5a1ff81f8a38a2c6df2b' 
  AND token = 'ONLB984XoU4NxYCVc5vFvuEaleGYz3O94MB4pxTPlCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}