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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac49fd11594b88c83de56d3806d4ec564f2f2cb1c8a806e7663c3a2d28b7a3fd' 
  AND token = 'tuQkOp/tYOXDLw5NJLFAex1ksn+Swc+4qX4vBxCjcJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}