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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a221f73ae2c0379bf5cd8b841f960b1583b02c11af07483ff3c63066a4c5fc12' 
  AND token = '5zydNARHdW2GI9M128VWLqCCR9Ncxlqu+jF5luuzjsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}