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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8d52a4d7ed91c8154576948bf4656f34dba427887501f370a34716b8b8745a6' 
  AND token = 'wF63y42rrd0W1ltKJROaIklDQXMkbrHoSTdPckLVnF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}