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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ec44fa4cac7888995f1d600c874232572af53a91f62de8a58dddd12634fdf38' 
  AND token = 'r+yj4EHop8ud7in0ghuCAZAN/2uGqtsXT0Wx66Sh3Ak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}