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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28d70a40d948e55593e3a7b791f0f68f522815cb4cc69019b8bfc6df7e900914' 
  AND token = 'Z9+cNDGDMDZ6yAXWPsdg7DWh0Upan1yFR28eV/Km7lg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}