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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7381007be36366854491b23a9c97b62ce0557a494e827bd0c55b56857be4478' 
  AND token = '/OOY9tCNjWk8/6hhMfPVHqNGXtYy2Big6EBF52ncHp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}