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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b50b3832735f8f42c667193097805a4af6cc51f95b810a33cf8857f59665f24' 
  AND token = 'Gpm5BogAqa35xg+W4icfsttv559pgbEHW/McizRi17c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}