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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8fa87b85b12a8e7188e1a5698f933055b80d054ca20d4df9e1bd790fb903040' 
  AND token = 'Vss3Y3c4W0MGw6nYxKrLrdjoD+pjA+SbNxek4ywihuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}