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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b4b6fea6c6ea62ecbe71c24740a16261e5865695c2e65af6c54d2ccb8083ad4' 
  AND token = 'C1LoeKM2IF7D+cKtLS+MGxULR1U1UakFIGB3j8uDpKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}