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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d0a231ec6b41abd5e3bf5ddc5ef5954f7840e074436317436a6049030a6e8fc' 
  AND token = 'Z5Q4T89KVoRwdH38pYXNoUNneSf/ti2CrhSNGIs1Vj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}