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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6375ecbb0587a7d9601d7e6783f6a5262c1892cd752c1e4de2ce27ca2252e69c' 
  AND token = 'hCeTUu44l4K4M+wDgfA170lnfsouf26Uq+iy0eI932M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}