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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e55910cba2e755174cf12693e06058038276e61d3eed20be39ba33aea06e887' 
  AND token = 'Zlz6Ffkl3e8lCIp4tz8EbM26hga/dD4j8FQEP6rD/Ms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}