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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '256a8980f78f7b2f75bfff2cc36a5ef2b5ed9c61bd8b2e25512205bfefdeaca2' 
  AND token = 'iXVoYnJpC5bj+BInh8tewBAZwptn/UQbf6djCY5/NUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}